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Nottingham

Multiple Sclerosis Research Group (MSRG)

  1. Home
  2. Research
  3. Nottingham MS Research Group
  4. Disease Modifying Therapies
  • Centres of excellence
  • Centre for Dementia
    • About us
    • Current Research
    • Events
    • Members of Centre for Dementia
  • Centre for Mental Health and Human Rights
    • About us
    • Current Research
    • Events
    • Members of Centre for Mental Health & Human Rights
    • WHO Collaborating Centre
  • Centre for Health and Justice
    • About us
    • Current Research
    • Members - Centre for Health and Justice
  • Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan (CANDAL)
    • About us
    • Current Research
    • Members of CANDAL
  • Centre for Mood Disorders
    • About Us
    • Current Research
    • Members of the Centre for Mood Disorders
  • Centre for Social Futures
    • About us
    • Current research
    • Members of SoFU
  • Centre for Translational Neuroscience
    • About Us
    • Current Research
    • Members of the Centre for Translational Neuroscience
  • MindTech
  • Projects and studies
    • CORAS
    • e-OPTIMISM
    • EXPAND
    • INDUCT
    • OPTIMISE
    • ORBIT-UK
    • PRESIDE
    • Research in Social Care for Older People (RSCOP)
    • SATURN
    • SMART MS
    • SMART MCI
    • SPARX
    • STADIA
    • TRIPOD
    • Waiting Well
    • WoW Study
      • Wellbeing of the workforce (WOW) study
      • Meet the team
      • Reports and Publications
      • Links and Resources
    • Completed studies
      • ADHD in Primary Care
      • AQUEDUCT
      • BRIGhTMIND
      • Covid 19 Studies
      • EME
      • Evaluating the care certificate
      • ExTRAPPOLATE
      • Far Away From Home
      • gameChange
      • NEON
      • NEON Good Practice Guidelines
      • ORBIT
      • ORCHARD
      • PRIDE
      • QUOTA
      • REBOOT
      • SAAND
      • UNFOLD 2
      • VOICE
      • WAIT study
  • Managed Innovation Networks
    • Apply
    • Current Projects
      • Enhancing ADHD awareness in schools
      • Surviving by storytelling
      • Wellbeing in the Woods
    • Completed projects
      • Arts and Trauma
      • Learning disability secure care network
      • Me thinking: Learning a new outlook in life
      • Youth mental health and wellbeing
      • Young adults living with learning disabilities
      • Trauma, resilience and growth
      • Studio House Choir
      • Post modern slavery
      • Respiratory Mentors
      • People's choir
      • Digital Technology for Mental Health: Asking the Right Questions
      • Mental Health and Psychological Wellbeing in Neurological Conditions
  • National Steering Group for Tics & Tourette Syndrome
    • About us
    • Who we are
    • Projects
    • Local, national and social media
    • Publications
    • Policy Brief
  • UK Mental Health Mission
  • Research Delivery Team
    • Portfolio of research delivery projects
    • Meet the team
    • Mood disorder studies
    • Dementia studies
    • Psychosis and schizophrenia studies
    • Forensic mental health studies
    • Learning and developmental disabilities studies
    • Physical health studies
    • Child and adolescent services studies
    • Perinatal and early years studies
    • Eating Disorder studies
    • Public health / COVID-19 studies
  • Forensic Research Nottingham
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    • Recent Publications
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Disease Modifying Therapies

 One of the main foci of our research is to explore new avenues in MS treatment and toOne of the main foci of our research is to explore new avenues in MS treatment and togain a greater understanding of how best to use our current disease modifyingtherapies (DMTs). There are 9 approved DMTs in the UK and more are becomingavailable every year. All of them aid in decreasing inflammation and it is thought theymight even protect neurons. All DMTs work with the overall aim to improve the clinicaloutcome of people with MS.DMTs have been found to decrease the number and severity of relapse, slow thedevelopment and progression of brain and spinal cord lesions, and reducedisabilities. However, there is currently little to no evidence on which type of DMT isbest, for which patients, and when would be the most beneficial time to use them toget the best results.Stronger treatments are usually associated with riskier side effects. Therefore, thequestion is, can we find the right balance of effectiveness and side effects? Our aim,working with many other MS research teams across the world, is to provide thisevidence in order to find the best treatment for each patient.

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Contact Us

Institute of Mental Health
University of Nottingham
Innovation Park
Jubilee Campus
Triumph Road
Nottingham
NG7 2TU

IMH@nottshc.nhs.uk

0115 823 1294

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