We are currently researching the following areas relating to psychosis and schizophrenia:

 

NEON: Personal experience as a recovery resource in psychosis: Narrative Experiences Online (NEON) Programme  – Phase 1.

Study summary:

Phase one of the NEON programme is to develop an understanding of how personal stories of mental health problems and recovery may help others. 
Participants will be invited to share their story of recovery in an interview with a researcher. The story will be recorded and anonymised, with each participant receiving £20 expenses.

We’d like to hear from people with experience of what may be called psychosis, eg hearing voices or seeing / believing things that others don’t AND who have not been in contact with NHS mental health services in recent years.

To find out more, email Lead Research Delivery Nurse - Jo Higman This email address is being protected from spambots. You need JavaScript enabled to view it. or text/call: 07920453729

The study was approved by Nottinghamshire Healthcare NHS Foundation Trust in May 2018.
Recruitment will continue until December 2018.

 

AppRoVE -  Assertive Responding to Voices: Evaluating the psychometric properties of new measures of responding to distressing voices and other people.

Local Principal Investigator:  Dr Mohammad Zia Katshu

Study summary: 

The AppRoVe study) is run by the University of Sussex and aims to evaluate the psychometric properties of two new measures of assertive responding to: 1) distressing voices (‘auditory hallucinations’); and 2) other people. 

The study was approved by Nottinghamshire Healthcare NHS Foundation Trust in May 2018
Recruitment will continue until April 2019.

Referral for this study must come through your care team.

For information contact Lead Research Delivery Officer – Dr Kate Bransby-Adams, Tel: 07769235480
This email address is being protected from spambots. You need JavaScript enabled to view it.

 

PPiP II – Prevalence of Pathogenic antibodies In Psychosis.

Principal Investigator: Dr Eileen O’Regan

The PPiP2 study (Prevalence of Pathogenic Antibodies in Psychosis) is an observational study running across 35 sites nationally. This clinical study follows on from research by the Oxford-based team who noted that psychosis is a common presenting feature in antibody-mediated encephalitis (inflammatory brain disease), and who showed in preliminary trials that treatment with immunotherapy usually led to remission.  

PPiP2 aims to establish how prevalent these membrane-receptor-antibodies are in patients who present with psychotic symptoms in mental health services.  For who those who test positive for these antibodies (by means of a blood test) immunotherapy may be an appropriate treatment. 

Thanks to the success of PPiP in establishing the presence of pathogenic antibodies in more than 7% of those tested, funding has been awarded to open clinical trials in four sites including Nottingham  to test the efficacy of immunotherapy as a treatment for antibody-mediated psychosis.   

The study was approved by Nottinghamshire Healthcare NHS Foundation Trust in August 2018

Recruitment will continue until August 2020.

Referral for this study must come through your care team.

For information contact Lead Research Delivery Officer – Dr Kate Bransby-Adams, Tel: 07769235480
This email address is being protected from spambots. You need JavaScript enabled to view it.

 

PATOM - Psychosis, Attention and Theory of Mind

Principal Investigator: Dr Eileen O’Regan

Study summary:

An observational study investigating the psychological mechanisms relating to psychosis, such as Theory of Mind.  Participants are invited to carry out a number of assessments, which may reveal if these mechanisms are implicated in specific symptoms of psychosis.   It is hoped that the findings will lead to increased understanding of psychotic disorders and inform the development of effective interventions.

This study is running in Nottinghamshire Healthcare NHS Foundation Trust but is no longer looking for new participants.

Contact: Lead Research Delivery Officer - Dr Kate Bransby-Adams, Tel: 07769235480
This email address is being protected from spambots. You need JavaScript enabled to view it.